Baltimore born, E. Donald Robb was the son of Eliakim Tupper and Mary (Campbell) Robb. He graduated from the Drexel Institute in 1899. He apprenticed in Philadelphia with
T. P. Chandler and
Cope & Stewardson before moving to New York to work with
Cram, Goodhue & Ferguson. From 1911 to 1914 he partnered with
Clarence W. Brazer, another Drexel graduate, in the firm of
Brazer & Robb but in 1914 returned to
Cram & Ferguson. His later firms were
Frohman & Robb and
Frohman, Robb & Little, the firm responsible for the National Episcopal Cathedral in Washington, DC.
Robb had conducted considerable study of medieval art and architecture, all of which supported his interest in ecclesiastical design.
He was a member of the AIA and of the Boston Society of Architects.